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Promotion by mixtures of dichloroacetic acid and trichloroacetic acid of N-methyl-N-nitrosourea-initiated cancer in the liver of female B6C3F1 mice

✍ Scribed by Michael A. Pereira; Kewa Li; Paula M. Kramer


Book ID
117468915
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
744 KB
Volume
115
Category
Article
ISSN
0304-3835

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The effect of dichloroacetic acid and tr
✍ Rongrong Ge; Siming Yang; Paula M. Kramer; Lianhui Tao; Michael A. Pereira πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 181 KB

## Abstract The chlorine disinfection by‐products, dichloroacetic acid (DCA) and trichloroacetic acid (TCA), are carcinogenic in mouse liver. We have previously reported that DCA and TCA induced DNA hypomethylation in mouse liver. In the present study, we determined the temporal association for DNA