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Loss of heterozygosity on chromosome 6 in dichloroacetic acid and trichloroacetic acid-induced liver tumors in female B6C3F1 mice

✍ Scribed by Lianhui Tao; Kewa Li; Paula M. Kramer; Michael A. Pereira

Book ID
117468355
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
731 KB
Volume
108
Category
Article
ISSN
0304-3835

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The effect of dichloroacetic acid and tr
The effect of dichloroacetic acid and trichloroacetic acid on DNA methylation and cell proliferation in B6C3F1 mice
✍ Rongrong Ge; Siming Yang; Paula M. Kramer; Lianhui Tao; Michael A. Pereira πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 181 KB

## Abstract The chlorine disinfection by‐products, dichloroacetic acid (DCA) and trichloroacetic acid (TCA), are carcinogenic in mouse liver. We have previously reported that DCA and TCA induced DNA hypomethylation in mouse liver. In the present study, we determined the temporal association for DNA