✦ LIBER ✦

Progress in the Pursuit of Therapeutic Adenosine Receptor Antagonists

✍ Scribed by Stefano Moro; Zhan-Guo Gao; Kenneth A. Jacobson; Giampiero Spalluto

Publisher: John Wiley and Sons
Year: 2006
Weight: 8 KB
Volume: 37
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200624268

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Recent developments in the field of A3 a

Recent developments in the field of A3 adenosine receptor antagonists

✍ Pier Giovanni Baraldi; Mojgan Aghazadeh Tabrizi; Francesca Fruttarolo; Andrea Bo 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 201 KB 👁 2 views

## Abstract Adenosine is an endogenous modulator of a large variety of physiological functions through the interaction with specific cell membrane G‐protein‐coupled receptors classified as A~1~, A~2A~, A~2B~, and A~3~. Activation of A~3~ receptors has been shown to stimulate phospholipase C and to

Potent antagonists for the human adenosi

Potent antagonists for the human adenosine A2B receptor. Derivatives of the triazolotriazine adenosine receptor antagonist ZM241385 with high affinity

✍ Maarten de Zwart; Roel C. Vollinga; Margot W. Beukers; Danielle F. Sleegers; Jac 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 147 KB 👁 2 views

A series of novel and known 5-substituted 7-amino-2-(2-furyl) [1,2,4]triazolo [1,5a][1,3,5]triazine derivatives were synthesized and tested for adenosine receptor antagonism in radioligand binding assays at all four adenosine receptor subtypes and for inhibition of the agonist-induced cyclic AMP res

The Discovery and Synthesis of Novel Ade

The Discovery and Synthesis of Novel Adenosine Receptor (A2A) Antagonists.

✍ Julius J. Matasi; John P. Caldwell; Jinsong Hao; Bernard Neustadt; Leyla Arik; C 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 21 KB 👁 2 views

Recent Developments in the Field of A2A

Recent Developments in the Field of A2A and A3 Adenosine Receptor Antagonists

✍ Pier Giovanni Baraldi; Mojgan Aghazadeh Tabrizi; Andrea Bovero; Barbara Avitabil 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 51 KB 👁 2 views

Highlights on the Development of A2A Ade

Highlights on the Development of A2A Adenosine Receptor Agonists and Antagonists

✍ Gloria Cristalli; Barbara Cacciari; Diego Dal Ben; Catia Lambertucci; Stefano Mo 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 11 KB 👁 1 views

Adenosine receptors involved in the bron

Adenosine receptors involved in the bronchoconstrictor effect of adenosine

✍ Guy F. Joos; Romain A. Pauwels 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 312 KB 👁 2 views

Adenosine may play a role in the airflow obstruction in asthma and chronic obstructive pulmonary disease. Although the mechanism of adenosine-induced bronchoconstriction has been well explored, little is known about the identity of adenosine-receptors involved. Studies on rabbit and rat airways sugg