𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Recent Developments in the Field of A2A and A3 Adenosine Receptor Antagonists

✍ Scribed by Pier Giovanni Baraldi; Mojgan Aghazadeh Tabrizi; Andrea Bovero; Barbara Avitabile; Delia Preti; Francesca Fruttarolo; Romeo Romagnoli; Katia Varani; Pier Andrea Borea


Publisher
John Wiley and Sons
Year
2003
Weight
51 KB
Volume
34
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Comparative molecular field analysis (Co
✍ Pier Giovanni Baraldi; Pier Andrea Borea; Manuela Bergonzoni; Barbara Cacciari; πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 304 KB πŸ‘ 2 views

Selective and potent antagonists for the A 2A adenosine receptors have been described recently. The most potent compounds have a triazolo-pyrimidine structure, whereas 8-styryl-xanthines usually possess lower affinity at the A 2A receptor. We have examined the quantitative structure activity relatio

A2A-selective adenosine receptor antagon
✍ Christa E. MΓΌller; Roland Sauer; Yuris Maurinsh; Rosa Huertas; Friederike FΓΌlle; πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 214 KB πŸ‘ 2 views

A 2A adenosine receptor (AR) antagonists are promising new drugs for the treatment of Parkinson's disease. Further potential therapeutic indications for A 2A AR antagonists include dementias, ischemias, and pain. Potent, selective A 2A AR antagonists have been developed, but their generally low wate

Pyran template approach to the design of
✍ An-Hu Li; Xiao-duo Ji; Hak Sung Kim; Neli Melman; Kenneth A. Jacobson πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 138 KB πŸ‘ 2 views

A 3 adenosine receptor antagonists have potential as anti-inflammatory, anti-asthmatic, and anti-ischemic agents. We previously reported the preparation of chemical libraries of 1,4-dihydropyridine (DHP) and pyridine derivatives and identification of members having high affinity at A 3 adenosine rec

Potent antagonists for the human adenosi
✍ Maarten de Zwart; Roel C. Vollinga; Margot W. Beukers; Danielle F. Sleegers; Jac πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 147 KB πŸ‘ 2 views

A series of novel and known 5-substituted 7-amino-2-(2-furyl) [1,2,4]triazolo [1,5a][1,3,5]triazine derivatives were synthesized and tested for adenosine receptor antagonism in radioligand binding assays at all four adenosine receptor subtypes and for inhibition of the agonist-induced cyclic AMP res