A step-wise CoMFA-based procedure was applied to a series of 51 C2-oxyadenosines in order to select the most predictive conformation for binding to A 2A adenosine receptor. The highest correlation and predictive power was found for conformers with the side chain at the 2position oriented in the dire
β¦ LIBER β¦
Highlights on the Development of A2A Adenosine Receptor Agonists and Antagonists
β Scribed by Gloria Cristalli; Barbara Cacciari; Diego Dal Ben; Catia Lambertucci; Stefano Moro; Giampiero Spalluto; Rosaria Volpini
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 11 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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