Profiling protein expression and interactions: proximity ligation as a tool for personalized medicine
✍ Scribed by A. Blokzijl; M. Friedman; F. Pontén; U. Landegren
- Book ID
- 108863774
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 680 KB
- Volume
- 268
- Category
- Article
- ISSN
- 0954-6820
No coin nor oath required. For personal study only.
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## Abstract Procedures and reagents are needed to specifically detect all the macromolecules that are being identified in the course of genome projects. We discuss how this challenge may be met using a set of ligation‐based reagents termed padlock probes and proximity ligation probes. These probes
## Abstract The sequentiation of the human genome, together with the development of high throughput technologies, particularly gene‐expression profiling, is giving us the opportunity to describe biological features in a quantitative manner. Here we review the use of global gene expression analyses