✦ LIBER ✦

Production of interleukin 8 by cultured synovial cells in response to interleukin 1 and tumor necrosis factor

✍ Scribed by K. Hirota; T. Akahoshi; H. Endo; H. Kondo; S. Kashiwazaki

Publisher: Springer
Year: 1992
Tongue: English
Weight: 384 KB
Volume: 12
Category: Article
ISSN: 0172-8172
DOI: 10.1007/bf00246871

No coin nor oath required. For personal study only.

✦ Synopsis

Both interleukin 1 alpha (IL-1 alpha) and tumor necrosis factor alpha (TNF alpha) stimulated the production of interleukin 8 (IL-8) by synovial cells in time and dose dependent manners. Enhanced chemotactic activity of polymorphonuclear cells (PMN) in culture supernatants of synovial cells was neutralized with anti-IL-8 antibody, thus showing synovial cells to be capable of secreting IL-8 which may contribute to PMN accumulation in rheumatoid inflamed joints.

📜 SIMILAR VOLUMES

Interleukin-8 production in response to

Interleukin-8 production in response to tumor necrosis factor-alpha by cholesteatoma keratinocytes in cell culture

✍ Christopher W. Hilton; Frank G. Ondrey; Beverley R. Wuertz; Samuel C. Levine 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 628 KB

## Abstract ## Objectives/Hypothesis: Keratinocytes harvested from acquired cholesteatoma and grown in cell culture will demonstrate increased interleukin‐8 (IL‐8) production in response to tumor necrosis factor (TNF)‐alpha as compared with a control keratinocyte cell line. Immunohistochemical stu

Ambroxol inhibits interleukin 1 and tumo

Ambroxol inhibits interleukin 1 and tumor necrosis factor production in human mononuclear cells

✍ M. Bianchi; A. Mantovani; A. Erroi; C. A. Dinarello; P. Ghezzi 📂 Article 📅 1990 🏛 SP Birkhäuser Verlag Basel 🌐 English ⚖ 356 KB

Expression of monocyte chemotactic and a

Expression of monocyte chemotactic and activating factor in rheumatoid arthritis. regulation of its production in synovial cells by interleukin-1 and tumor necrosis factor

✍ Tohru Akahoshi; Chieki Wada; Hirahito Endo; Kazuhisa Hirota; Shigeru Hosaka; Ken 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 939 KB

Reduction of tumor necrosis factor α and

Reduction of tumor necrosis factor α and interleukin-1β levels in human synovial tissue by interleukin-4 and glucocorticoid

✍ A. Bendrups; A. Hilton; A. Meager; J. A. Hamilton 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 418 KB

Interleukin-1α and tumor necrosis factor

Interleukin-1α and tumor necrosis factor α synergistically stimulate prostaglandin E2-dependent production of interleukin-11 in rheumatoid synovial fibroblasts

✍ Takemine Mino; Eiji Sugiyama; Hirofumi Taki; Arihiko Kuroda; Naohiro Yamashita; 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 768 KB

Differential regulation of rheumatoid sy

Differential regulation of rheumatoid synovial cell interleukin-12 production by tumor necrosis factor α and CD40 signals

✍ Minetake Kitagawa; Hiroshi Mitsui; Hiroshi Nakamura; Shinichi Yoshino; Shunpei M 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 202 KB 👁 2 views