Expression of monocyte chemotactic and activating factor in rheumatoid arthritis. regulation of its production in synovial cells by interleukin-1 and tumor necrosis factor
β Scribed by Tohru Akahoshi; Chieki Wada; Hirahito Endo; Kazuhisa Hirota; Shigeru Hosaka; Kenji Takagishi; Hirobumi Kondo; Sadao Kashiwazaki; Kouji Matsushima
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 939 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective At sites of inflammation, T cells exert pathologic effects through direct contact with monocyte/macrophages, inducing massive upβregulation of interleukinβ1 (ILβ1) and tumor necrosis factor Ξ± (TNFΞ±). We examined the regulatory effects of ILβ18 on monocyte activation by dir
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