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Production, Binding and Cytotoxicity of Human/Mouse Chimeric Monoclonal Antibody-Neocarzinostatin Conjugate

✍ Scribed by Yamaguchi, Toshiharu ;Tsurumi, Hiroshi ;Kitamura, Kazuya ;Otsuji, Eigo ;Miyagaki, Takuya ;Kotani, Tatsuya ;Takahashi, Toshio

Book ID
108579752
Publisher
Wiley (Blackwell Publishing)
Year
1993
Tongue
English
Weight
281 KB
Volume
84
Category
Article
ISSN
0910-5050

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## Abstract Hybridoma CE7 produces a murine antibody (yl/k) which binds to a 190‐kDa cell‐surface glycoprotein of human neuroblas‐toma. Because of its tumor specificity, it has been used routinely in clinical pathology to confirm diagnosis of neuroblastoma. We have Isolated the gene segments coding