𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Process considerations for the asymmetric synthesis of chiral amines using transaminases

✍ Scribed by Pär Tufvesson; Joana Lima-Ramos; Jacob S. Jensen; Naweed Al-Haque; Watson Neto; John M. Woodley


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
422 KB
Volume
108
Category
Article
ISSN
0006-3592

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Asymmetric synthesis of chiral amines wi
✍ Jong-Shik Shin; Byung-Gee Kim 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 108 KB

The asymmetric synthesis of chiral amines using prochiral ketones was carried out with (S)-specific -transaminase (-TA) from Vibrio fluvialis JS17. This reaction is inhibited severely by both products, (S)-amine and deaminated ketone. In addition, thermodynamic equilibrium strongly favored the rever

Engineering aromatic L-amino acid transa
✍ Byung-Kwan Cho; Joo-Hyun Seo; Taek-Jin Kang; Juhan Kim; Hyung-Yeon Park; Bon-Su 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 176 KB

An enzymatic asymmetric synthesis was carried out for the preparation of enantiomerically pure L-diphenylalanine using the rationally engineered aromatic L-amino acid transaminase (eAroATEs) obtained from Enterobacter sp. BK2K-1. To rationally redesign the enzyme, structural model was constructed by