The asymmetric synthesis of chiral amines using prochiral ketones was carried out with (S)-specific -transaminase (-TA) from Vibrio fluvialis JS17. This reaction is inhibited severely by both products, (S)-amine and deaminated ketone. In addition, thermodynamic equilibrium strongly favored the rever
✦ LIBER ✦
Process considerations for the asymmetric synthesis of chiral amines using transaminases
✍ Scribed by Pär Tufvesson; Joana Lima-Ramos; Jacob S. Jensen; Naweed Al-Haque; Watson Neto; John M. Woodley
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 422 KB
- Volume
- 108
- Category
- Article
- ISSN
- 0006-3592
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Asymmetric synthesis of chiral amines wi
✍
Jong-Shik Shin; Byung-Gee Kim
📂
Article
📅
1999
🏛
John Wiley and Sons
🌐
English
⚖ 108 KB
Efficient Asymmetric Synthesis of Chiral
Efficient Asymmetric Synthesis of Chiral Amines by Combining Transaminase and Pyruvate Decarboxylase
✍
Matthias Höhne; Steffen Kühl; Karen Robins; Uwe T. Bornscheuer
📂
Article
📅
2008
🏛
John Wiley and Sons
🌐
English
⚖ 232 KB
Stereoselectivity of Four (R)-Selective
✍
Francesco G. Mutti; Christine S. Fuchs; Desiree Pressnitz; Johann H. Sattler; Wo
📂
Article
📅
2011
🏛
John Wiley and Sons
🌐
English
⚖ 218 KB
Necessary and sufficient conditions for
✍
Joo-Hyun Seo; Dohyun Kyung; Keehyoung Joo; Jooyoung Lee; Byung-Gee Kim
📂
Article
📅
2010
🏛
John Wiley and Sons
🌐
English
⚖ 439 KB
👁 1 views
Asymmetric, Catalytic Synthesis of α-Chi
✍
Alessandro A. Boezio; Julien Pytkowicz; Alexandre Cote; Andre B. Charette
📂
Article
📅
2004
🏛
John Wiley and Sons
⚖ 191 KB
## Abstract For Abstract see ChemInform Abstract in Full Text.
Engineering aromatic L-amino acid transa
✍
Byung-Kwan Cho; Joo-Hyun Seo; Taek-Jin Kang; Juhan Kim; Hyung-Yeon Park; Bon-Su
📂
Article
📅
2006
🏛
John Wiley and Sons
🌐
English
⚖ 176 KB
An enzymatic asymmetric synthesis was carried out for the preparation of enantiomerically pure L-diphenylalanine using the rationally engineered aromatic L-amino acid transaminase (eAroATEs) obtained from Enterobacter sp. BK2K-1. To rationally redesign the enzyme, structural model was constructed by