The asymmetric synthesis of chiral amines using prochiral ketones was carried out with (S)-specific -transaminase (-TA) from Vibrio fluvialis JS17. This reaction is inhibited severely by both products, (S)-amine and deaminated ketone. In addition, thermodynamic equilibrium strongly favored the rever
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Efficient Asymmetric Synthesis of Chiral Amines by Combining Transaminase and Pyruvate Decarboxylase
✍ Scribed by Matthias Höhne; Steffen Kühl; Karen Robins; Uwe T. Bornscheuer
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 232 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1439-4227
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