Asymmetric, Catalytic Synthesis of α-Chiral Amines Using a Novel Bis(phosphine) Monoxide Chiral Ligand.
✍ Scribed by Alessandro A. Boezio; Julien Pytkowicz; Alexandre Cote; Andre B. Charette
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 191 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
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📜 SIMILAR VOLUMES
The rhodium complex prepared in situ by simply mixing [[RhCl(c-octene)2]2] and [(Phebox)SnMe3] (1) (Phebox = 2,6-bis(oxazolinyl)phenyl) was found to serve as an efficient catalyst for the asymmetric Michael addition of alpha-cyanopropionates (4) to acrolein under mild and neutral conditions. In the
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