Novel Asymmetric Michael Addition of α-Cyanopropionates to Acrolein by the Use of a Bis(oxazolinyl)phenylstannane-Derived Rhodium(III) Complex as a Chiral Lewis Acid Catalyst.

Novel Asymmetric Michael Addition of α-C

Novel Asymmetric Michael Addition of α-Cyanopropionates to Acrolein by the Use of a Bis(oxazolinyl)phenylstannane-Derived Rhodium(III) Complex as a Chiral Lewis Acid Catalyst

✍ Yukihiro Motoyama; Yoshiyuki Koga; Kouji Kobayashi; Katsuyuki Aoki; Hisao Nishiy 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 170 KB 👁 1 views

The rhodium complex prepared in situ by simply mixing [[RhCl(c-octene)2]2] and [(Phebox)SnMe3] (1) (Phebox = 2,6-bis(oxazolinyl)phenyl) was found to serve as an efficient catalyst for the asymmetric Michael addition of alpha-cyanopropionates (4) to acrolein under mild and neutral conditions. In the

Novel Asymmetric Michael Addition of α-Cyanopropionates to Acrolein by the Use of a Bis(oxazolinyl)phenylstannane-Derived Rhodium(III) Complex as a Chiral Lewis Acid Catalyst.

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Abstract