## Abstract ## Background and Objective Photodynamic therapy (PDT) is FDAβapproved antiβcancer modality for elimination of early disease and palliation in advanced disease. PDT efficacy depends in part on elicitation of a tumorβspecific immune response that is dependent on cytotoxic T lymphocytes
Probing the stability of class I major histocompatibility complex (MHC) molecules on the surface of human cells
β Scribed by M. Edidin; Sharon Achilles; Richard Zeff; Taiyin Wei
- Publisher
- Springer-Verlag
- Year
- 1997
- Tongue
- English
- Weight
- 112 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0093-7711
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Mutants that had lost expression of alleles of one or more HLA loci were isolated with immunoselection after gamma-irradiation of a human lymphoblastoid cell line LCL 721. DNAs from the mutants were digested with restriction endonucleases and analyzed by Southern blotting using probes for class I HL