Effect of invariant chain on major histocompatibility complex class I molecule expression and stability on human breast tumor cell lines
โ Scribed by Xuede Lin; Xiaojian Wang; Haley L. Capek; Laura C. Simone; Amit Tuli; Chantey R. Morris; Adrian J. Reber; Joyce C. Solheim
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 381 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0340-7004
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The expression of products encoded by the major histocompatibility complex ( M H C ) on tumor cells has recently been studied exrensively. It has been found that many malignant tumor cells have their MHC antigens 'switched-off but that these antigens are re-expressed following DNA-mediated gene tran
## Abstract ## Background and Objective Photodynamic therapy (PDT) is FDAโapproved antiโcancer modality for elimination of early disease and palliation in advanced disease. PDT efficacy depends in part on elicitation of a tumorโspecific immune response that is dependent on cytotoxic T lymphocytes
## Abstract The spontaneous expression of HLA classโI and classโII molecules in 5 human breast carcinoma cell lines, MCFโ7, T47D, ZR75โI, HSLโ53, MDAโMB 231, and their modulation during IFNโ~ฮณ~ treatment, are reported. The expression of cellโsurface determinants was examined by indirect immunofluor