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Prevention of neuroleptic-induced dopamine D2 receptor supersensitivity by chronic iron salt treatment

✍ Scribed by Dorit Ben-Shachar; Bilha Pinhassi; Moussa B.H. Youdim

Book ID
115886833
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
819 KB
Volume
202
Category
Article
ISSN
0014-2999

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Chronic neuroleptic treatment: D2 dopami
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✍ Dr Paolo Calabresi; Marco De Murtas; Nicola Biagio Mercuri; Giorgio Bernardi πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 807 KB

## Abstract We studied the in vitro electrical activity of rat neostriatal neurons following chronic neuroleptic treatment. In haloperidol‐treated rats, unlike naive animals, activation of neostriatal D2 dopamine receptors induced a potent presynaptic inhibition of glutamate‐mediated excitatory syn