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Inhibition of neuroleptic-induced dopamine receptor supersensitivity by cyclo (Leu-Gly)

✍ Scribed by Hemendra N. Bhargava; Ronald F. Ritzmann


Book ID
113218061
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
409 KB
Volume
13
Category
Article
ISSN
0091-3057

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Different neuroleptics caused dopamine receptor blockade (antagonism against methylphenidate-induced compulsive gnawing) for varying lengths of time. When the receptor blockade had expired, supersensitivity to dopamine agonists (occurrence of apomorphine-induced compulsive gnawing and enhancement of