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Pretreatment with 5-FU enhances cisplatin cytotoxicity in head and neck squamous cell carcinoma cells

โœ Scribed by Kei Ijichi; Makoto Adachi; Yasuhisa Hasegawa; Tetsuya Ogawa; Hideaki Nakamura; Ayumi Kudoh; Yoshihiro Yasui; Shingo Murakami; Kanji Ishizaki


Book ID
105992812
Publisher
Springer
Year
2007
Tongue
English
Weight
541 KB
Volume
62
Category
Article
ISSN
0344-5704

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Cisplatin is a widely used chemotherapeutic agent in head and neck squamous cell carcinoma (HNSCC). Resistance to cisplatin is a common feature of HNSCC. To identify genes that may regulate cisplatin sensitivity, we carried out a cDNA microarray analysis of gene expression in cisplatin-sensitive and