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Caspase-9 regulates cisplatin-induced apoptosis in human head and neck squamous cell carcinoma cells

✍ Scribed by Daisuke Kuwahara; Kouichiro Tsutsumi; Tetsuya Kobayashi; Tomoko Hasunuma; Kusuki Nishioka

Book ID: 117469670
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 362 KB
Volume: 148
Category: Article
ISSN: 0304-3835
DOI: 10.1016/s0304-3835(99)00315-8

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## Abstract Cisplatin is a chemotherapeutic agent that is widely used to treat cancers such as head and neck squamous cell carcinoma (HNSCC). Previously, we have reported that cisplatin induced an early caspase‐dependent apoptosis (8 hr) in a HNSCC cell, HN4. In this study, we examined a late caspa

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