Fenretinide-induced apoptosis of human head and neck squamous carcinoma cell lines
โ Scribed by RICHARD L. SCHER; WILFRED SAITO; RICHARD K. DODGE; WILLIAM J. RICHTSMEIER; ROBERT L. FINE
- Book ID
- 117403312
- Publisher
- SAGE Publications
- Year
- 1998
- Tongue
- English
- Weight
- 324 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0194-5998
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๐ SIMILAR VOLUMES
Nonfunctional p53 and especially upregulation of Bcl-x(L) result in advanced disease and poor prognosis of patients suffering head and neck squamous cell carcinoma (HNSCC). Aberrancies of Bcl-x(L) and/or p53 in HNSCC lead to inability of anticancer drugs to induce apoptosis. Bcl-x(L) and/or mutated
## Abstract ## __Background.__ We established multiple University of Michigan Squamous Cell Carcinoma (UMโSCC) cell lines. With time, these have been distributed to other labs all over the world. Recent scientific discussions have noted the need to confirm the origin and identity of cell lines in