Combination Chemotherapy With Cisplatin and Peplomycin in Squamous Cell Carcinoma of the Head and Neck
β Scribed by Inuyama, Yukio; Fujii, Masato; Tanaka, Juichi; Takaoka, Tetsuro; Hosoda, Hyonosuke; Kohno, Naoyuki; Saito, Shigeji
- Book ID
- 122020634
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 518 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0385-8146
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A combination of cisplatin, methotrexate, bleomycin, and vincristine (CABO) was assessed in advanced epidermoid head and neck cancer. Among 72 patients with recurrent or metastatic disease and measurable lesions, there were 9 complete and 27 partial responses for an overall response rate of 50%. The
## Abstract Fiftyβone patients (32 previously untreated, 19 previously treated) with advanced squamous cell carcinoma of the head and neck received a single course of combination chemotherapy consisting of high dose __cis__βplatinum (DDP), bleomycin (Bleo), Β± high dose methotrexate (MTX). Thirtyβth
## For the EORTC Head and Neck Cooperative Group A total of 185 eligible patients with advanced inoperable squamous cell carcinoma of the head and neck were randomized into two groups; the cisplatin, methotrexate, bleomycin, and vincristine (CABO) group received cisplatin (50 mg/m2; day 4), methot