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Preparation of phosphopeptide thioesters by Fmoc- and Fmoc(2-F)-solid phase synthesis

✍ Scribed by Koki Hasegawa; YinLin Sha; JeongKyu Bang; Toru Kawakami; Kenichi Akaji; Saburo Aimoto


Book ID
110346631
Publisher
Springer Netherlands
Year
2001
Tongue
English
Weight
104 KB
Volume
8
Category
Article
ISSN
1573-3149

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πŸ“œ SIMILAR VOLUMES


Direct preparation of peptide thioesters
✍ Xiangqun Li; Toru Kawakami; Saburo Aimoto πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 266 KB

Aiming at the direct preparation of peptide thioesters by an Fmoc solid-phase method, we searched a new deblocking reagent, which efficiently removed Fmoc groups while keeping the thioester intact. The deblocking reagent, which contains 1-methylpyrrolidine, hexamethyleneimine and HOBt in a one to on

Peptide thioester preparation by Fmoc so
✍ Andrew B. Clippingdale; Colin J. Barrow; John D. Wade πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 135 KB πŸ‘ 2 views

Established methodology for the preparation of peptide thioesters requires the use of t-butoxycarbonyl chemistry owing to the lability of thioester linkers to the nucleophilic reagents used in Fmoc solid phase peptide synthesis. Both the greater ease of use and the broad applicability of the method