๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Preparation of phosphopeptide thioesters by Fmoc-and Fmoc(2-F)-solid phase synthesis

โœ Scribed by Koki Hasegawa; Yin Lin Sha; Jeong Kyu Bang; Toru Kawakami; Kenichi Akaji; Saburo Aimoto


Publisher
Springer Netherlands
Year
2001
Tongue
English
Weight
505 KB
Volume
8
Category
Article
ISSN
1573-3149

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Direct preparation of peptide thioesters
โœ Xiangqun Li; Toru Kawakami; Saburo Aimoto ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 266 KB

Aiming at the direct preparation of peptide thioesters by an Fmoc solid-phase method, we searched a new deblocking reagent, which efficiently removed Fmoc groups while keeping the thioester intact. The deblocking reagent, which contains 1-methylpyrrolidine, hexamethyleneimine and HOBt in a one to on

Peptide thioester preparation by Fmoc so
โœ Andrew B. Clippingdale; Colin J. Barrow; John D. Wade ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 135 KB ๐Ÿ‘ 2 views

Established methodology for the preparation of peptide thioesters requires the use of t-butoxycarbonyl chemistry owing to the lability of thioester linkers to the nucleophilic reagents used in Fmoc solid phase peptide synthesis. Both the greater ease of use and the broad applicability of the method

An improved deblocking agent for direct
โœ Xianzhang Bu; Guiyang Xie; Chi Wang Law; Zhihong Guo ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 133 KB

To synthesize peptide thioesters directly on a solid support for use as substrate analogues for thioesterases in non-ribosomal peptide synthases, we modified a reagent compatible with Fmoc solid-phase peptide synthesis that efficiently removes the protecting group while keeping the thioester intact.