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Preparation of Chiral Oxazolidin-2-ones and Vicinal Amino Alcohols

✍ Scribed by Takacs, James M.; Jaber, Mohamad R.; Vellekoop, A. Samuel


Book ID
121272095
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
94 KB
Volume
63
Category
Article
ISSN
0022-3263

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Synthesis of chiral oxazolidin-2-ones by
✍ Marta Feroci; Armando Gennaro; Achille Inesi; Monica Orsini; Laura Palombi πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 French βš– 316 KB

An improved electrochemical synthesis of chiral oxazolidin-2-ones from chiral 1,2-amino alcohols is obtained by direct electrolysis of solutions of MeCN-TEAP containing the amino alcohol, with subsequent CO 2 bubbling and addition of TsCl. This synthesis avoids any addition of bases or probases and