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Synthesis of new chiral N-arylsulfonyl-1,3-oxazolidin-2-ones from α-amino acids

✍ Scribed by Ahmed Ould Aliyenne; Jamil Kraïem; Yakdhane Kacem; Béchir Ben Hassine


Book ID
108109650
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
224 KB
Volume
10
Category
Article
ISSN
1631-0748

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Effective Methods for the Synthesis of N
✍ Andrew B. Hughes; Brad E. Sleebs 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 German ⚖ 278 KB

N-Methyl b-amino acids are generally required for application in the synthesis of potentially bioactive modified peptides and other oligomers. Previous work highlighted the reductive cleavage of 1,3-oxazolidin-5-ones to synthesise N-methyl a-amino acids. Starting from a-amino acids, two approaches w