Preparation of an asymmetrically protected phosphoramidite and its application in solid-phase synthesis of phosphopeptides
✍ Scribed by Zoltán Kupihár; Györgyi Váradi; Éva Monostori; Gábor K Tóth
- Book ID
- 108379783
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 120 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
Oligoribonucleotides, six to fifteen units long, were synthesized on a controlled pore glass support using ribonucleoside 3'-0-phosphoramidite reagents. Average coupling yieids of up to 98% were obtained with dirsopropylamrnophosphoramidite derivatives. In light of the increasing interest in the ro
The syntheses of N,N-diisopropylmethylphosphoramidites (3a,b) of 9-I [Zdimethoxytrityl-hydroxy-l-(hydroxymethyl)ethoxy]-methyl)N6-benzoyladenine, 2a, and l-{ [Zdimethoxytritylhydroxy-1-(hydroxymethyl)ethoxy]-methyl)thymine, 2b, are described. Oligoacyclonucleotides, 2 -8 units long, were synthesized