𝔖 Bobbio Scriptorium
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Preparation of an unprotected phosphotyrosine building block and its application in solid-phase synthesis of phosphopeptides

✍ Scribed by Christian Krog-Jensen; Mette K. Christensen; Morten Meldal


Book ID
110268587
Publisher
Springer Netherlands
Year
1999
Tongue
English
Weight
58 KB
Volume
6
Category
Article
ISSN
1573-3149

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An Improved Synthesis of a Galactosylate
✍ BjΓΆrn Holm; Johan Broddefalk; Sara Flodell; Eric Wellner; Jan Kihlberg πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 French βš– 151 KB

Different protective groups for (5R)-5-hydroxy-l-lysine were investigated in silver silicate promoted glycosylations with acetobromogalactose as glycosyl donor. Best results were obtained with Fmoc-Hyl(Cbz)-OAll, which was glycosylated in 80% yield. Removal of the allyl group gave a b-d-galactosylat