Deoxyribosides of thymine and uracil labelled with 14C of specife activity identical with that of the original radioactive base were prepared by single-step enzymatic synthesis. When employing 2-deoxyy-cr,-D-riboso-I-phosphate of dicyclohexylamine salt, the enzymatic preparation isolated .from Esche
Preparation of 5-halogeno derivatives of deoxyuridine labelled in the base with 14C
✍ Scribed by J. Filip; Z. Nejedly
- Publisher
- John Wiley and Sons
- Year
- 1969
- Tongue
- French
- Weight
- 380 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract [2‐^14^C]5‐Allyl‐2′‐deoxyuridine was synthesized directly from [2‐^14^C]2′‐deoxyuridine using mercury, palladium, and 3‐chloropropene. [2‐^14^C]5‐Propyl‐2′‐deoxyuridine was obtained by hydrogenation of the [^14^C]5‐allyl‐2′‐deoxy‐uridine. Advantages of the synthetic method and its appli
UNNATURAL NUCLEOSIDES AND NUCLEOTIDES. III.
For metabolic studies in this Laboratory, 5-hydroxytryptamine (serotonin) labelled with I4C in the pyrrole part of the indole ring was required. Previous attempts to reach this compound through Madelung cyclization of 3-benzyloxy--6-formylaminotoluene failed (I), although this way proved to be succe