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Preparation and pharmacokinetics of 11C labeled stavudine (d4T)

โœ Scribed by Eli Livni; Mark Berker; Shawn Hillier; Stephen C Waller; Marc D Ogan; Robert P Discordia; J.Kent Rienhart; Robert H Rubin; Alan J Fischman


Book ID
116798740
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
207 KB
Volume
31
Category
Article
ISSN
0969-8051

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๐Ÿ“œ SIMILAR VOLUMES


Synthesis of 1โ€ฒ-[14C]-stavudineยฎ (d4T)
โœ Robert P. Discordia ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 485 KB ๐Ÿ‘ 2 views

1-(1'-[14C1-2',3'-Dideoxy-~-~glyceropent-2'-enofuranosy~~thymine (1'-114C1-d4T), was synthesized kom l-[14Cl-ribose, 1, in 7 steps in an overall yield of 29.3%. 1-[14C]-Ribose was converted in one step to l-O-methy1-2,3,5-tri-O-benzoylribofuranoside 2 in quantitative yield. Compound 2 was converted

The preparation of 11C-labeled caffeine
โœ H. R. Denutte; T. Vandewalle; H. J. Cattoir; C. Vandecasteele; J. A. Jonckheere; ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 229 KB

## Abstract A rapid and mild procedure for the preparation of [Nโ€7โ€methylโ€^11^C] caffeine is described. Gaseous ^11^Cโ€methyl iodide wa led into dimethyl sulphoxide (DMSO), containing theophylline (1,3โ€dimethylaxanthine) and sodium hydride. Purification of the reaction product was achieved by High P