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Preparation and investigation of [14C]padimate-O and [14C]N-nitroso-N-nor-padimate-O

✍ Scribed by Anita H. Lewin; Louise Fudala

Publisher
John Wiley and Sons
Year
1995
Tongue
French
Weight
353 KB
Volume
36
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Carbonation of the aryl lithium obtained from p‐N,N(dimethylamino)bromobenzene with carbon‐14 labeled carbon dioxide, followed by esterification gave [CO~2~‐^14^C]p‐N,N(dimethylamino)benzoate 2‐ethylhexyl ester (Padimate‐O). This material underwent slow decomposition to [^14^C]N‐nor‐Padimate‐O and [^14^C]N‐formyl‐N‐nor‐Padimate‐O. Nitrosation of [^14^C]Padimate‐O with sodium nitrite afforded [^14^C]N‐nitroso‐N‐nor‐Padimate‐O.

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