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Prad-1 gene amplification in head and neck squamous cell carcinoma

โœ Scribed by Klijanienko, J.; Bianchi, A.B.; El-Naggar, A.; Janot, F.; Luboinski, B.; Conti, C.J.; Cvitkovic, E.

Book ID
122079413
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
169 KB
Volume
29
Category
Article
ISSN
0959-8049

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## Background. Abnormalities in chromosome llq13 regions have been frequently found in head and neck squamous carcinoma. Recent studies indicate that the PRAD-1 (also CCNDI), which encodes cyclin D1, is a putative oncogene that is an important component of this region. Methods. DNA was extracted

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