Practical preparation of 4(R)-allylazetidinones and 4(R)-(1-methylallyl)azetidinones
β Scribed by Fliri, Hans; Mak, Ching Pong
- Book ID
- 126136215
- Publisher
- American Chemical Society
- Year
- 1985
- Tongue
- English
- Weight
- 673 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A stereoselective synthesis of (1 0 S,3R,4R)-4-acetoxy-3-(2 0 -fluoro-1 0 -trimethylsilyloxyethyl)-2-azetidinone as a new fluorine-containing intermediate towards b-lactams, is described. The synthetic key step relies upon the dynamic kinetic resolution (DKR) of ethyl 2-benzamidomethyl-4-fluoro-3-ox
A short stereoselective synthesis of the acetoxy azetidinone (1), an important precursor of several biologically active β€-lactam antibiotics, has been accomplished in seven steps and 32.8% overall yield from the easily available and inexpensive (R) ethyl 3-hydroxybutanoate.