ChemInform Abstract: Preparation of (3S,4S)-1-Benzhydryl-3-[(5R)-1′-hydroxyethyl]-4-acyl-2-azetidinones from (2R,3R)-Epoxybutyramide Precursors.
✍ Scribed by Bo-Liang Deng; Marc Demillequand; Mathieu Laurent; Roland Touillaux; Marc Belmans; Luc Kemps; Marcel Ceresiat; Jacqueline Marchand-Brynaert
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 34 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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Methoxycyclitol 4 was acetalized in a non-classical one-pot idene moiety was realised in two steps via the corresponding ethylidene acetals 8 and 9; the ethylidene function was procedure with chloral/dicyclohexylcarbodiimide forming the 4-epi derivative 6. The stepwise deprotection of removed with a