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Population genetics of glyoxalase I (E.C.4.4.1.5) in human erythrocytes

✍ Scribed by Berg, Konrad ;Rodewald, Alexander ;Schwarzfischer, Friedrich ;Wischerath, Hans


Publisher
Springer-Verlag
Year
1977
Tongue
English
Weight
140 KB
Volume
79
Category
Article
ISSN
1437-1596

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✦ Synopsis


1025 individuals from Southern Germany were examined. The gene frequencies for GLI1 are 0.4235 and for GLI2 0.5765. These frequencies are compared with those of other authors.


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Red cell glyoxalase I (E.C.: 4.4.1.5): F
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The polymorphism of glyoxalase I was investigated in 169 mother-child combinations from southwestern Germany. Glyoxalase I (GLO) has 3 common phenotypes: GLO 1, GLO 2-1, and GLO 2. The results are in good agreement with the formal hypothesis: Two alleles GLO1 and GLO2 at an autosomal locus. The GLO1

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The phenotypes of glyoxalase I (GLO) were determined in a random population from Hessen (Germany) by high-voltage agarose gel electrophoresis. The gene frequencies in 1150 unrelated individuals were 0.4391 for GLO1 and 0.5609 fro GLO2. Rare phenotypes were not observed. The segregation of phenotypes