Population genetics of glyoxalase I (E.C.4.4.1.5) in human erythrocytes
β Scribed by Berg, Konrad ;Rodewald, Alexander ;Schwarzfischer, Friedrich ;Wischerath, Hans
- Publisher
- Springer-Verlag
- Year
- 1977
- Tongue
- English
- Weight
- 140 KB
- Volume
- 79
- Category
- Article
- ISSN
- 1437-1596
No coin nor oath required. For personal study only.
β¦ Synopsis
1025 individuals from Southern Germany were examined. The gene frequencies for GLI1 are 0.4235 and for GLI2 0.5765. These frequencies are compared with those of other authors.
π SIMILAR VOLUMES
The segregation of GLO-phenotypes was analysed in 119 families with 266 children. The results are in agreement with the formal two-allele-model. Close linkage was ruled out for a number of informative markers.
The polymorphism of glyoxalase I was investigated in 169 mother-child combinations from southwestern Germany. Glyoxalase I (GLO) has 3 common phenotypes: GLO 1, GLO 2-1, and GLO 2. The results are in good agreement with the formal hypothesis: Two alleles GLO1 and GLO2 at an autosomal locus. The GLO1
The phenotypes of glyoxalase I (GLO) were determined in a random population from Hessen (Germany) by high-voltage agarose gel electrophoresis. The gene frequencies in 1150 unrelated individuals were 0.4391 for GLO1 and 0.5609 fro GLO2. Rare phenotypes were not observed. The segregation of phenotypes