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Investigations on the polymorphism of glyoxalase I (EC 4.4.1.5) in the population of Hessen, Germany

✍ Scribed by P. Kühnl; R. Schwabenland; W. Spielmann

Publisher
Springer
Year
1977
Tongue
English
Weight
390 KB
Volume
38
Category
Article
ISSN
0340-6717

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✦ Synopsis

The phenotypes of glyoxalase I (GLO) were determined in a random population from Hessen (Germany) by high-voltage agarose gel electrophoresis. The gene frequencies in 1150 unrelated individuals were 0.4391 for GLO1 and 0.5609 fro GLO2. Rare phenotypes were not observed. The segregation of phenotypes in 50 families and 32 mother-child combinations supports the assumed autosomal codominant inheritance. The possibility of a simultaneous typing for GLO, esterase D (EsD), and carbonic anhydrase2 (CA2) on one gel is discussed.

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