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Properdin factor B-polymorphism in the population of Hessen, Germany

✍ Scribed by K�hnl, P. ;Spielmann, W.

Publisher
Springer-Verlag
Year
1978
Tongue
English
Weight
624 KB
Volume
81
Category
Article
ISSN
1437-1596

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✦ Synopsis

The polymorphism of properdin factor B (Bf, C3 proactivator) in a population sample from Hessen, Germany has been investigated by agarose gel electrophoresis and immunofixation. In 522 unrelated individuals seven different phenotypes were observed and the following allele frequencies calculated: BfS = 0.7998, BfF = 0.1772, BfS0.7 = 0.0163 and BfF1 = 0.0077. Investigations of 100 families with 198 children and 30 mother-child combinations support the assumed autosomal codominant way of inheritance.

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