Polymorphism of red cell glyoxalase I (E.C.: 4.4.1.5). A new genetic marker in man
✍ Scribed by J. Kömpf; S. Bissbort; S. Gussmann; H. Ritter
- Publisher
- Springer
- Year
- 1975
- Tongue
- English
- Weight
- 151 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0340-6717
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✦ Synopsis
The polymorphism of glyoxalase I was investigated in 169 mother-child combinations from southwestern Germany. Glyoxalase I (GLO) has 3 common phenotypes: GLO 1, GLO 2-1, and GLO 2. The results are in good agreement with the formal hypothesis: Two alleles GLO1 and GLO2 at an autosomal locus. The GLO1 gene frequency was estimated to be 0.39. From the electrophoretic pattern the GLO-molecule appears to consist of two subunits.
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