Polytetrahydrofuran Cross-Linked Polystyrene Resins for Solid-Phase Organic Synthesis
β Scribed by Toy, Patrick H.; Reger, Thomas S.; Garibay, Patrick; Garno, Jayne C.; Malikayil, J. A.; Liu, Gang-yu; Janda, Kim D.
- Book ID
- 121822625
- Publisher
- American Chemical Society
- Year
- 2001
- Tongue
- English
- Weight
- 160 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1520-4766
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π SIMILAR VOLUMES
Polystyrene resins containing flexible tetrahydrofuran derived cross-linkers are presented. These cross-linkers were designed to render the resins more 'organic solvent-like' and thus impart increased swelling/solvation characteristics in the resins with regard to common solvents used in solid-phase
The synthesis of three hydrophobic peptides, which are partial sequences of thioredoxin, on a newly developed, flexible 1,6-hexanediol diacrylate cross-linked polystyrene, in good yield and purity, is described.