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Polymorphisms of cytotoxic T lymphocyte-associated antigen-4 and cytokine genes in Taiwanese patients with ankylosing spondylitis

✍ Scribed by W.-Y. Lee; Y.-H. Chang; M.-K. Lo; C.-P. Chang; S.-C. Yang; T.-P. Yang; K.-T. Ho; C.-W. Juan; M.-Y. Shiau


Book ID
110893128
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
516 KB
Volume
75
Category
Article
ISSN
0001-2815

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The CTLA-4 gene encodes a T-cell receptor that is involved in the regulation of T-cell activation. Recent studies have demonstrated an association of a microsatellite polymorphism [variant lengths of a dinucleotide (AT)n repeat] lying in exon 3 of the CTLA-4 gene, specifically a 106-bp allele, with