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Cytotoxic T lymphocyte-associated antigen-4 polymorphism in patients with rheumatic heart disease

✍ Scribed by N. Düzgün; T. Duman; F. E. Haydardedeoğlu; H. Tutkak


Book ID
110893067
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
457 KB
Volume
74
Category
Article
ISSN
0001-2815

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The CTLA-4 gene encodes a T-cell receptor that is involved in the regulation of T-cell activation. Recent studies have demonstrated an association of a microsatellite polymorphism [variant lengths of a dinucleotide (AT)n repeat] lying in exon 3 of the CTLA-4 gene, specifically a 106-bp allele, with