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Association of CT60 cytotoxic T lymphocyte antigen-4 gene polymorphism with thyroid autoantibody production in patients with Hashimoto's and postpartum thyroiditis

✍ Scribed by K. Zaletel; B. Krhin; S. Gaberšček; A. Biček; T. Pajič; S. Hojker


Book ID
108701182
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
179 KB
Volume
161
Category
Article
ISSN
0009-9104

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The CTLA-4 gene encodes a T-cell receptor that is involved in the regulation of T-cell activation. Recent studies have demonstrated an association of a microsatellite polymorphism [variant lengths of a dinucleotide (AT)n repeat] lying in exon 3 of the CTLA-4 gene, specifically a 106-bp allele, with