Polymorphisms in the Hypoxia Inducible Factor 1-α and the Impact on the Prognosis of Early Stages of Oral Cancer
✍ Scribed by Mario Fernando Muñoz-Guerra; María Encarnación Fernández-Contreras; Ana Laura Capote Moreno; Irene Domínguez Martín; Belén Herráez; Carlos Gamallo
- Book ID
- 111773057
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 295 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1068-9265
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## Background: Hypoxia-inducible factor (hif)1 alpha is considered to play a key role in the adaptation of cells to hypoxia by stimulating angiogenesis via regulation of vascular endothelial growth factor and by metabolic adaptation to o(2) deprivation. ## Methods: Expression of hif-1 alpha prote