## Background: Hypoxia-inducible factor (hif)1 alpha is considered to play a key role in the adaptation of cells to hypoxia by stimulating angiogenesis via regulation of vascular endothelial growth factor and by metabolic adaptation to o(2) deprivation. ## Methods: Expression of hif-1 alpha prote
Expression of hypoxia-inducible factor-1α in oligodendrogliomas : Its impact on prognosis and on neoangiogenesis
✍ Scribed by Dirk Vordermark
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 247 KB
- Volume
- 94
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
✦ Synopsis
better if the lactate dehydrogenase value was withdrawn from the staging system proposal.
Clinical staging systems are developed to provide accurate prognostic information for diagnostic therapeutic decision-making and, moreover, to facilitate communication between clinicians. Therefore, clinical staging systems must not be too complicated and should be based on a limited number of features. We suggest simplifying the AJCC staging system proposal by the points mentioned above to alleviate the classification of melanoma patients and simplify clinical communication.
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