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Polymorphisms in the adenomatous polyposis coli (APC) gene and advanced colorectal adenoma risk

✍ Scribed by Hui-Lee Wong; Ulrike Peters; Richard B. Hayes; Wen-Yi Huang; Arthur Schatzkin; Robert S. Bresalier; Ellen M. Velie; Lawrence C. Brody

Book ID
116430405
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
187 KB
Volume
46
Category
Article
ISSN
0959-8049

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Several investigators have reported germline mutations of the APC gene in patients with familial adenomatous polyposis (FAP) as well as somatic mutations in tumors developed in digestive organs (stomach, pancreas, colon, and rectum). Those results provide evidence that inactivation of the APC gene p

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