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Polymorphisms in NFKBIA and ICAM-1 genes in New Zealand Caucasian Crohn's disease patients

✍ Scribed by Jiwon Hong; Euphemia Leung; Alan G Fraser; Tony R Merriman; Prakash Vishnu; Geoffrey W Krissansen

Book ID: 108951469
Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 84 KB
Volume: 22
Category: Article
ISSN: 0815-9319
DOI: 10.1111/j.1440-1746.2007.05020.x

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## Background: To investigate the contribution of multidrug resistance 1 (MDR1) gene pharmacogenetics (G2677T/A and C3435T) to the efficacy of azathioprine in inducing remission in patients with Crohn's disease (CD). ## Methods: A cohort of 327 unrelated Spanish patients with CD recruited from