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Polymorphisms in the organic cation transporter genes SLC22A4 and SLC22A5 and Crohn's disease in a New Zealand Caucasian cohort

✍ Scribed by LEUNG, EUPHEMIA; HONG, JIWON; FRASER, ALAN G; MERRIMAN, TONY R; VISHNU, PRAKASH; KRISSANSEN, GEOFFREY W


Book ID
108944567
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
55 KB
Volume
84
Category
Article
ISSN
0818-9641

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## Communicated by Richard G.H. Cotton A common haplotype spanning 250 kb on chromosome 5q31 is strongly associated with Crohn disease (CD). Recently, two functional variants within the SLC22A4 and SLC22A5 genes at this locus (IBD5), L503F (c.1507C4T) and G-207C (c.-207G4C), have been proposed to