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Polymorphisms of CARD15/NOD2 and CD14 genes in New Zealand Crohn's disease patients

✍ Scribed by Leung, Euphemia; Hong, Jiwon; Fraser, Alan G; Merriman, Tony R; Vishnu, Prakash; Abbott, William GH; Krissansen, Geoffrey W

Book ID: 108944522
Publisher: Nature Publishing Group
Year: 2005
Tongue: English
Weight: 79 KB
Volume: 83
Category: Article
ISSN: 0818-9641
DOI: 10.1111/j.1440-1711.2005.01362.x

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## Background: Three mutations (r702w, g908r, and 1007fs) of the card15/nod2 gene associate with crohn's disease (cd). despite a strong linkage of cd to the inflammatory bowel disease (ibd) 1 region, only 16% of the finnish cd patients carry 1 of these 3 mutations, pointing to the possibility of ye