𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Polymorphism in the 3′-untranslated region of the thymidylate synthase gene and sensitivity of stomach cancer to fluoropyrimidine-based chemotherapy

✍ Scribed by Jian-Wei Lu; Chang-Ming Gao; Jian-Zhong Wu; Hai-Xia Cao; Kazuo Tajima; Ji-Feng Feng


Book ID
106251974
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
204 KB
Volume
51
Category
Article
ISSN
1435-232X

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Single nucleotide polymorphism in the 5′
✍ Eugenio Marcuello; Albert Altés; Elisabeth del Rio; Angeles César; Anna Menoyo; 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 84 KB 👁 1 views

## Abstract Thymidylate synthase (TS) is the primary target of 5‐fluorouracil (5‐FU). A VNTR polymorphism in the TS promoter region is associated with the efficacy of 5‐FU‐based chemotherapy in colorectal cancer. A common G>C SNP at the 12th nucleotide of the second repeat in the TS\*3 alleles has

Effect of polymorphisms in the 3′ untran
✍ Tomomitsu Tahara; Tomoyuki Shibata; Masakatsu Nakamura; Hiromi Yamashita; Daisuk 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 98 KB

## Abstract A complex interaction of host genetic and environmental factors may be relevant in the development of __Helicocobacter pylori__‐related gastric carcinogenesis. We investigated the effect of vascular endothelial growth factor (VEGF) gene polymorphisms on the risk of gastric cancer (GC) a