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The combination of ERCC1 and XRCC1 gene polymorphisms better predicts clinical outcome to oxaliplatin-based chemotherapy in metastatic colorectal cancer

✍ Scribed by Jun Liang; Tao Jiang; Ru-yong Yao; Zi-min Liu; Hong-ying Lv; Wei-wei Qi

Publisher
Springer
Year
2009
Tongue
English
Weight
205 KB
Volume
66
Category
Article
ISSN
0344-5704

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✍ Xiaobo Lu; Sha Xiao; Cuihong Jin; Tahar van der Straaten; Xiaoxia Li 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 464 KB

Our purpose is to evaluate the predictive value of the genetic polymorphisms of Excision repair cross-complementing group 1 (ERCC1) and xeroderma pigmentosum group D/excision repair crosscomplementing group 2 (XPD/ERCC2) in patients with advanced colorectal cancer receiving oxaliplatin-based chemoth