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Polymeric micelles from poly(ethylene glycol)-poly(amino acid) block copolymer for drug and gene delivery

✍ Scribed by Osada, K.; Christie, R. J.; Kataoka, K.


Book ID
111655713
Publisher
The Royal Society
Year
2009
Tongue
English
Weight
423 KB
Volume
6
Category
Article
ISSN
1742-5689

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## Abstract Thermosensitive PNVCL‐__b__‐PEG block copolymer coupled with folic acid was prepared as an anti‐cancer drug carrier. This polymer self‐assembled into stable micelles in aqueous solutions at above 33 °C. At 37 °C, the release profile of PNVCL‐__b__‐PEG‐FA micelles showed a slower and mor